Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/25/2025

Vyvanse and Urinary Function

Clinical Evaluation and Monitoring

  • The American Urological Association suggests evaluating for unrelated urological conditions such as urethral stricture, bladder outlet obstruction, or neurogenic bladder dysfunction that may coincidentally occur during ADHD treatment 1
  • The American Academy of Pediatrics recommends considering comorbid conditions including anxiety or depression, and screening for substance use in adolescents and young adults, as substances of abuse can affect lower urinary tract function independently of ADHD medications 2
  • Monitoring of blood pressure and pulse is recommended at baseline and regularly during stimulant treatment, as cardiovascular effects are well-established side effects of amphetamines 4

Treatment and Side Effects

  • The treatment of ADHD with stimulants like Vyvanse may result in patients experiencing common side effects including decreased appetite, insomnia, and headache, which are more likely explanations for patient complaints than urinary symptoms 2