Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/10/2025

Myxedema Coma Precipitating Factors

Precipitating Factors (Critical Triggers)

  • Surgery represents a major physiologic stressor that can precipitate myxedema coma 1
  • Trauma or injury can also precipitate myxedema coma 1
  • Hypoglycemia must be identified and corrected immediately, according to the American Academy of Clinical Endocrinologists 2

Myxedema Coma Precipitating Factors

Radiation Therapy History

  • The National Comprehensive Cancer Network recommends inquiring about radiation therapy to the neck region for any malignancy, as this can contribute to the development of myxedema coma 3

REFERENCES

2

Treatment of Myxedema Coma [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

hodgkin lymphoma version 1.2017, nccn clinical practice guidelines in oncology. [LINK]

Journal of the National Comprehensive Cancer Network : JNCCN, 2017