Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 7/10/2025

Chronic Pain Management

Patient Selection Criteria

  • Patients with chronic pain duration exceeding 12 months, pain severity of 9/10 on VAS scale, documented functional impairment, and failure of multiple conservative treatments are eligible for spinal cord stimulation trial 1
  • Specific qualifying conditions for spinal cord stimulation include failed back surgery syndrome with significant radicular pain, complex regional pain syndrome, inoperable chronic ischemic limb pain, or specific neuropathic pain conditions, as recommended by the Aetna Clinical Policy Bulletin 2

Interventional Procedures

  • Dorsal column stimulation is recommended as an intervention for refractory pain when other treatments have failed, according to the National Comprehensive Cancer Network 1
  • Spinal cord stimulation can provide significant pain relief in patients with chronic back and leg pain, particularly those with lumbosacral radiculopathy and failed back surgery syndrome 3
  • The surgical approach to implant the new stimulator in the same location as the existing one is appropriate, as recommended by the American Society of Anesthesiologists 4

Expected Outcomes

  • Patients can reasonably expect significant pain reduction (target of at least 50% reduction), improved functional status, reduced reliance on opioid medications, and enhanced quality of life with spinal cord stimulation 1
  • A successful spinal cord stimulator trial would demonstrate at least 50% reduction in pain intensity, improved function and mobility, enhanced ability to perform activities of daily living, and reduced need for pain medications 4

Trial Procedure

  • The trial procedure for spinal cord stimulation should involve percutaneous placement of trial leads under fluoroscopic guidance, intraoperative testing to ensure adequate paresthesia coverage of painful areas, and a 5-7 day trial period to assess efficacy 1
  • Intraoperative nerve monitoring is essential to ensure spinal cord safety during the procedure, according to the American Academy of Neurology 5
  • Proper anchoring of the leads is crucial to prevent migration, which could necessitate revision, as reported in the literature 4

Multidisciplinary Management Approach

  • Chronic pain syndrome requires a comprehensive biopsychosocial assessment and a multidisciplinary team approach for effective management, as recommended by the British Pain Society 6
  • The American College of Physicians recommends considering physical exercise and functional training to reduce pain symptoms, as evidence supports its efficacy in chronic low back pain management 7
  • Cognitive behavioral therapy (CBT) is a recommended non-pharmacological intervention for chronic pain syndrome, as suggested by the American College of Physicians and the British Pain Society 7, 6
  • Low-dose tricyclic antidepressants or serotonin-norepinephrine reuptake inhibitors have proven efficacy for chronic pain, and neuromodulators should be started at low doses and titrated gradually, as recommended by the American Gastroenterological Association 8

Complications and Follow-up

  • Lead migration is a potential complication, and careful planning and execution of the procedure can help minimize this risk, as recommended by the North American Neuromodulation Society 4
  • Documented device failure, such as cut spinal cord stimulator leads during a procedure, renders the device non-functional, according to the American Academy of Neurology 5
  • Regular follow-up is necessary to assess device function and pain control, and to monitor for any signs of infection or other complications, as recommended by the American Pain Society 4
  • Optimizing medication regimens, particularly focusing on non-opioid options, is recommended by the American Pain Society and the American College of Physicians 7