Corticosteroid Treatment for Severe Croup
Dosing Recommendations
- The maximum dose of prednisolone should not exceed 60 mg 1, 2
- Prednisolone should be given as a single morning dose to minimize adrenocortical suppression 3
Administration Considerations
- Oral administration is preferred unless the child is vomiting or in severe respiratory distress, and for children unable to take oral medication, intramuscular dexamethasone should be considered as an alternative 3
Distinguishing Croup Steroid Dosing from Asthma Steroid Dosing
Dosing Guidance
- Do not apply asthma steroid regimens (1–2 mg/kg per day for multiple days) to croup; the recommended regimen for croup is a single oral dose of prednisolone 1 mg/kg. This clarification helps avoid dosing errors between two distinct respiratory conditions. 4