Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/14/2025

Knee Replacement Implant Design Selection

Implant Design Variations

  • The American Academy of Orthopaedic Surgeons provides strong evidence that there is no clinically meaningful difference between major implant design variations in total knee arthroplasty—cemented versus uncemented fixation, all-polyethylene versus modular tibial components, and posterior-stabilized versus cruciate-retaining designs all produce equivalent outcomes, complications, and revision rates 1, 2

Component Fixation

  • Strong evidence supports using either cemented or uncemented tibial component fixation with similar long-term survivorship 1
  • Moderate evidence confirms equivalent outcomes when comparing all-cemented versus all-uncemented femoral and tibial components 1, 2

Tibial Component Design

  • No difference exists in pain, function, or revision rates between all-polyethylene and modular tibial component designs 1

Patellar Resurfacing

  • Pain and functional outcomes are equivalent whether the patella is resurfaced or not 1
  • Patellar resurfacing may reduce the need for revision surgery beyond 5 years postoperatively 1
  • Strong evidence shows no difference in outcomes or complications with intraoperative navigation compared to conventional instrumentation 1, 3
  • Patient-specific instrumentation provides no benefit in pain, function, or alignment over conventional techniques 1, 2
  • Robotic systems increase operative time without improving long-term clinical outcomes or survivorship 3

Risk Factor Considerations

  • Strong evidence supports that obese patients have less improvement in outcomes with TKA, requiring preoperative counseling about realistic expectations 1
  • Moderate evidence shows patients with diabetes are at higher risk for complications 1
  • Moderate evidence indicates patients with chronic pain conditions have less improvement in patient-reported outcomes 1
  • Limited evidence suggests patients with depression/anxiety symptoms experience less improvement in outcomes 1

REFERENCES

1

surgical management of osteoarthritis of the knee: evidence-based guideline. [LINK]

The Journal of the American Academy of Orthopaedic Surgeons, 2016

2

Total Knee Arthroplasty Component Selection [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

Robotic Total Knee Replacement Systems [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025