Irbesartan Pharmacology and Clinical Applications

Introduction to Irbesartan

• The brand drug name for irbesartan is Avapro (also marketed as Aprovel in some countries) 1
• Standard dosing ranges from 150-300 mg once daily 1

Combination Therapy

• Irbesartan is available in combination with hydrochlorothiazide (a thiazide diuretic) for enhanced blood pressure control 2
• The combination product is marketed as Avalide 2

Safety Profile

• Irbesartan should be avoided during pregnancy due to potential fetal harm 3, 4