Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/13/2025

Lamotrigine Dosing for Pediatric Patients

Weight-Based Dosing

  • For children 6-12 years weighing 20-34 kg, a dose of 50 mg twice daily has been shown to achieve adequate serum concentrations, according to the American Thoracic Society 1, 2
  • For adolescents 13 years and older weighing at least 35 kg, a dose of 100 mg twice daily is recommended, based on guidelines from the American Thoracic Society 1, 2
  • Children weighing less than 20 kg may require case-by-case dosing considerations, as suggested by the American Thoracic Society 2