Fall Risk Associated with Pregabalin and Gabapentin

Risk Factors and Vulnerable Populations

The American Geriatrics Society recommends that elderly patients, patients with renal impairment, and those taking multiple medications be carefully considered when prescribing pregabalin or gabapentin due to increased fall risk 1
Patients with pre-existing mobility issues are also at higher risk of falls when taking these medications, according to the American Geriatrics Society 1

The American Geriatrics Society suggests reviewing all medications and considering alternatives when possible to mitigate fall risk in patients taking pregabalin or gabapentin 1
Medication reduction should be considered for patients taking four or more medications, as recommended by the American Geriatrics Society 1
Patient education and monitoring are crucial, with the American Geriatrics Society recommending that patients be warned about potential dizziness and somnolence, and that they be advised to exercise caution with tasks requiring alertness 1

The American Geriatrics Society recommends assessing baseline fall risk, considering alternatives if fall risk is high, and reviewing and potentially modifying other medications before prescribing pregabalin or gabapentin 1
When initiating treatment, the American Geriatrics Society suggests starting with the lowest effective dose, educating the patient about fall risk and precautions, and considering a home safety assessment for high-risk patients 1
During treatment, the American Geriatrics Society recommends monitoring for adverse effects, reassessing regularly for continued need and optimal dosing, and considering deprescribing if falls occur or risk becomes unacceptable 1