Treatment of Premenstrual Dysphoric Disorder (PMDD)
Pharmacologic Treatment
- The American College of Physicians recommends Alprazolam (benzodiazepine) for PMDD treatment, to be used cautiously due to dependence risk 1
- The American Academy of Family Physicians suggests NSAIDs for physical pain symptoms in PMDD patients 1
- The American College of Obstetricians and Gynecologists recommends monitoring for treatment-emergent suicidality, as SSRIs carry black box warnings for suicidality in adolescents and young adults 1, 2
Non-Pharmacologic Interventions
- The American College of Sports Medicine recommends regular aerobic exercise as a first-line treatment option for mild-to-moderate PMDD symptoms 1