Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/22/2025

Diagnosis of Paget's Disease of Bone

Laboratory Evaluation

  • Routine measurement should include alkaline phosphatase, calcium, 25-hydroxy-vitamin D, phosphate, and parathyroid hormone levels to exclude other metabolic bone diseases, as recommended by the Annals of the Rheumatic Diseases 1, 2