Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/22/2025

Citalopram Discontinuation in Young Patients

Introduction to Citalopram Discontinuation

  • The American Academy of Child and Adolescent Psychiatry recommends a gradual dose reduction of citalopram over several weeks to avoid withdrawal syndrome, which can be characterized by dizziness, fatigue, lethargy, and other symptoms 1

Protocol for Discontinuation

  • The American Academy of Child and Adolescent Psychiatry suggests avoiding discontinuation during periods of stress or significant life changes for the patient 2
  • It is recommended to inform the patient of potential withdrawal symptoms so they can recognize them 3

Special Considerations

  • Young patients may be more sensitive to the effects of discontinuation and require an even more gradual dose reduction 2
  • The American Academy of Child and Adolescent Psychiatry recommends monitoring for signs of suicidal ideation, particularly during the discontinuation period 3

Monitoring and Emergency Consultation

  • The American Academy of Child and Adolescent Psychiatry advises monitoring for the appearance of withdrawal symptoms, especially within 24 to 48 hours following each dose reduction 1
  • If severe symptoms such as suicidal ideation, extreme agitation, or severe physical symptoms appear, it is recommended to consult an emergency doctor 2
  • In case of serotonin syndrome (confusion, agitation, tremors, hyperreflexia, muscle rigidity, hypertension, tachycardia), the American Academy of Child and Adolescent Psychiatry recommends seeking immediate medical attention 1