Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/9/2025

Dietary Recommendations for Individuals with Elevated Liver Enzymes

Introduction to Dietary Recommendations

  • The Mediterranean diet is strongly recommended for individuals with elevated liver enzymes, as it has been shown to reduce liver fat and improve inflammation in non-alcoholic fatty liver disease, which is a common cause of elevated liver enzymes, according to the Journal of Hepatology 1
  • Elevated AST and ALT levels typically indicate liver inflammation or injury, with common causes including non-alcoholic fatty liver disease, alcoholic liver disease, viral hepatitis, medication-induced liver injury, and muscle injury 1

Dietary Components

  • Emphasize plant-based foods, such as vegetables, fruits, and legumes, as part of a healthy diet 2
  • Include whole grains rather than refined grains in your diet 3
  • Use extra virgin olive oil as the main added fat, and consume fish 2-3 times weekly, especially oily fish like salmon, sardines, and trout 2
  • Limit red meat consumption to reduce the risk of liver disease 2

Limiting Unhealthy Intake

  • Avoid processed foods and beverages with added fructose, and limit added sugars to no more than 100-150 kcal/day (6-9 teaspoons) 2, 3
  • Limit sodium intake to 2300 mg/day, and saturated fat to 5-6% of total calories 3
  • Reduce or eliminate alcohol consumption, especially with signs of advanced liver disease, as recommended by the Journal of Hepatology 1

Increasing Healthy Intake

  • Eat vegetables with all main meals, and choose whole grain varieties of breads and cereals 2
  • Include legumes 2-3 times weekly, and consume fresh fruit daily 2
  • Consume nuts and seeds as snacks, and replace saturated fats with polyunsaturated fatty acids (PUFAs) and monounsaturated fatty acids (MUFAs) 2

Weight Management

  • For overweight or obese individuals with elevated liver enzymes, aim for 5-7% weight loss to reduce liver fat, 7-10% weight loss to improve liver inflammation, and >10% weight loss to improve fibrosis, as recommended by the Journal of Hepatology 1
  • Focus on sustained weight loss through dietary changes rather than rapid weight loss, which can temporarily worsen liver enzymes 1

Lifestyle Recommendations

  • Engage in regular aerobic physical activity, such as at least 150 minutes of moderate-intensity exercise weekly, as recommended by the Journal of Hepatology and Drugs 1, 5
  • Drink at least 1.5 liters of water daily, and prefer baking, steaming, grilling, or boiling instead of frying 4
  • Keep a food and symptom journal to identify individual food sensitivities, and consider periodic assessment of nutritional status, particularly for vitamin and mineral deficiencies if dietary restrictions are significant 4