Management of Jaccoud's Arthropathy
Treatment Approach
- The American College of Rheumatology recommends considering adding methotrexate or azathioprine for inadequate response to first-line therapy, as these immunosuppressants are used for non-renal lupus manifestations 1
- For refractory cases, mycophenolate mofetil (MMF) has shown superiority over azathioprine in extrarenal SLE, though cost and teratogenicity are considerations 1
- Early recognition and treatment initiation are crucial, as emphasized by the Annals of the Rheumatic Diseases, to prevent progression of JA deformities 1
- Regular monitoring for progression and aggressive control of any underlying inflammatory activity are essential for effective management, as recommended by the Annals of the Rheumatic Diseases 1