Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/27/2025

Treatment of Endomyocardial Fibrosis

Introduction to Treatment

  • Surgical intervention with endocardial decortication and valve replacement/repair is the definitive treatment for endomyocardial fibrosis, as medical therapy alone has no curative benefit and the disease carries a very poor prognosis without surgery, according to the American Heart Association 1

Diagnostic Approach

  • Endomyocardial biopsy can confirm the diagnosis when EMF is suspected on clinical grounds, though the procedure should only be performed when results will meaningfully affect therapeutic decisions, as recommended by the American College of Cardiology 1, 2, 3