Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/22/2025

Differential Diagnosis for Golfer's Elbow (Medial Epicondylitis)

Primary Diagnosis

  • Medial epicondylitis (golfer's elbow) is a degenerative tendinopathy of the common flexor-pronator origin at the medial epicondyle, affecting 1-3.8% of the general population, most commonly between ages 40-60 1

Differential Diagnoses with Physical Exam Findings

Medial Compartment Pathologies

  • The American College of Radiology recommends pain with valgus stress testing of the elbow as a diagnostic criterion for UCL injury 3
  • Medial joint line tenderness (distinct from epicondyle) is a diagnostic finding for UCL injury 3
  • A positive moving valgus stress test in throwing athletes is indicative of UCL injury 3
  • The Journal of the American College of Radiology suggests that ulnar nerve subluxation with elbow flexion/extension is a diagnostic finding for cubital tunnel syndrome 4

Intra-articular Pathologies

  • Mechanical symptoms such as locking, clicking, or catching are indicative of intra-articular pathology, including osteochondral lesions (capitellum or medial trochlea) 3, 2
  • Limited range of motion and effusion may be present in osteochondral lesions 3, 2
  • Pain with passive range of motion (differentiates from tendinopathy) is a diagnostic finding for intra-articular loose bodies 2

Relevant Workup

Initial Imaging

  • The American College of Radiology recommends plain radiographs of the elbow as the most appropriate initial imaging study to rule out osseous pathology 3, 2, 1
  • Standard AP and lateral views can identify intra-articular bodies, heterotopic ossification, osteochondral lesions, soft tissue calcification within tendons, and occult fractures 2, 1

Advanced Imaging (When Radiographs Normal/Nonspecific)

  • MRI elbow without contrast is indicated for suspected tendon tear, nerve entrapment, or soft tissue pathology with normal radiographs 3, 2, 1
  • T2-weighted MR neurography is the reference standard for imaging ulnar nerve entrapment, showing high signal intensity and nerve enlargement 3, 4
  • MR arthrography elbow (3T) is the most accurate for UCL tears, with 81% sensitivity, 91% specificity, and 88% accuracy 3, 5, 6

Electrodiagnostic Studies

  • EMG and nerve conduction studies are indicated when neurologic symptoms suggest cubital tunnel syndrome, pronator syndrome, or posterior interosseous nerve syndrome 2

Key Clinical Pearls

Red Flags Requiring Further Investigation

  • Night pain or pain at rest suggests inflammatory or neoplastic process 2
  • Mechanical symptoms (locking, catching) indicate intra-articular pathology 3, 2
  • Neurologic symptoms (paresthesias, weakness) require nerve evaluation 2

Common Pitfalls

  • Overreliance on corticosteroid injections without addressing underlying biomechanical issues 1
  • Failing to obtain initial radiographs to rule out osseous pathology 2, 1

REFERENCES

1

Management of Medial Epicondylitis [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

acr appropriateness criteria® chronic elbow pain. [LINK]

Journal of the American College of Radiology, 2022

3

acr appropriateness criteria® chronic elbow pain. [LINK]

Journal of the American College of Radiology, 2022

4

Lateral Epicondylitis Management [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

5

acr appropriateness criteria® chronic elbow pain. [LINK]

Journal of the American College of Radiology, 2022

6

acr appropriateness criteria® chronic elbow pain. [LINK]

Journal of the American College of Radiology, 2022