Ondansetron Dosing Guidelines for Children

Weight-Based Dosing

• For children ≤15 kg, the American Academy of Pediatrics recommends 30 mg twice daily for treatment 1, 2
• For children >15-23 kg, the American Academy of Pediatrics recommends 45 mg twice daily for treatment 1, 2
• For children >23-40 kg, the American Academy of Pediatrics recommends 60 mg twice daily for treatment 1, 2
• For children >40 kg, the American Academy of Pediatrics recommends 75 mg twice daily for treatment 1, 2

Special Considerations

• For children with renal impairment, the Centers for Disease Control and Prevention recommends no dosage adjustment 3, 4
• For children, the Centers for Disease Control and Prevention recommends no dosage reduction based on age alone 3, 4

Practical Dosing Tips

• The American Academy of Pediatrics recommends rounding doses according to available formulations for ease of administration 5