Evaluation of Burr Cells (Echinocytes) and Large Platelets

Diagnostic Priorities for Echinocytes

Urgent Exclusion of Thrombotic Microangiopathy (TMA)

Hemolysis Assessment

Pyruvate Kinase (PK) Deficiency

Laboratory Work‑Up Algorithm (General)

Large Platelet Assessment

Myelodysplastic Syndromes (MDS) Consideration