Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/4/2025

Management of Chronic Shortness of Breath

Initial Assessment

  • The American College of Cardiology recommends confirming that previous cardiac workup remains relevant by checking for any new cardiac symptoms or changes in clinical presentation 1
  • The American Thoracic Society suggests evaluating asthma control status by assessing frequency of symptoms, medication compliance, and potential exacerbating factors 2, 3
  • The American Academy of Allergy, Asthma, and Immunology recommends assessing for possible dysfunctional breathing patterns which can mimic or exacerbate asthma symptoms, particularly in patients with anxiety 3, 4
  • The American Thoracic Society suggests considering performing spirometry to objectively measure current lung function and response to bronchodilators 3

Asthma Management

  • The National Asthma Education and Prevention Program recommends optimizing controller medications according to current guidelines, ensuring patient is on appropriate inhaled corticosteroids (ICS) with or without long-acting beta-agonists (LABAs) 2
  • The American Academy of Allergy, Asthma, and Immunology suggests providing short-acting beta-agonists (SABAs) for rescue therapy, but monitoring for overuse which may indicate poor asthma control 3
  • The American Academy of Allergy, Asthma, and Immunology recommends considering adding leukotriene modifiers which can be used daily or intermittently to prevent exercise-induced bronchoconstriction without leading to tolerance 3, 5

Anxiety Management

  • The American Thoracic Society suggests that for acute anxiety episodes with associated dyspnea, short-acting benzodiazepines such as alprazolam may be beneficial, particularly when panic symptoms are present 2
  • The American Psychiatric Association recommends considering buspirone starting at 5 mg twice daily (maximum 20 mg three times daily), which is particularly effective for anxiety in patients with chronic respiratory conditions 2, 6

Non-Pharmacological Interventions

  • The American Thoracic Society recommends implementing pulmonary rehabilitation which combines cardiovascular fitness, self-confidence building, and stress control techniques 2
  • The American Thoracic Society suggests teaching relaxation techniques such as yoga which may help manage both anxiety and dyspnea 2
  • The American Thoracic Society recommends considering oxygen therapy during exercise if desaturation is documented, as this can increase exercise capacity 2
  • The American Academy of Allergy, Asthma, and Immunology suggests providing education on dysfunctional breathing patterns and techniques to normalize breathing during anxiety episodes 3, 4

Follow-Up Plan

  • The American Academy of Allergy, Asthma, and Immunology recommends scheduling regular follow-up visits to assess response to therapy and adjust treatment as needed 3
  • The American College of Cardiology suggests reassessing cardiac status if symptoms change or worsen despite optimal management of asthma and anxiety 1
  • The American Thoracic Society recommends considering home pulse oximetry monitoring to objectively assess oxygen saturation during symptomatic episodes 2

Pitfalls and Caveats

  • The American College of Cardiology warns against attributing all symptoms to anxiety without thoroughly excluding organic causes, especially in elderly patients 1, 4
  • The American Thoracic Society cautions against long-term use of benzodiazepines due to risk of dependence and potential respiratory depression in patients with underlying lung disease 2