Lens Dislocation/Subluxation as an Ocular Emergency

Clinical Significance and Complications

Lens subluxation may be associated with retinal complications including retinal pigment epithelium disruption, chorioretinal atrophy, and retinal hemorrhaging 1

Patients presenting with lens dislocation/subluxation require immediate ophthalmologic assessment as they may represent an important clinical indicator of an embolic, inflammatory, or other process requiring urgent systemic medical evaluation 3
Diffusion-weighted MRI should be performed urgently (within 24 hours) in cases where vascular etiology is suspected, as silent brain infarction is frequently present in patients with acute ocular vascular symptoms 4

Lens subluxation may be a manifestation of systemic conditions including Marfan syndrome, characterized by long, thin build with wide-looking faces, high palate, and long fingers 5
Lens subluxation may be a manifestation of systemic conditions including Zika virus infection, particularly in congenital cases 1