Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/24/2025

Ankle Hyperinversion Injury: Most Commonly Injured Ligament

Mechanism and Epidemiology

  • Inversion injuries of the ankle represent 25% of all musculoskeletal injuries and 50% of sports-related injuries 1
  • The American College of Radiology reports that the anterior talofibular ligament (ATFL) is the most commonly injured ligament in ankle sprains caused by hyperinversion of the foot 1, 2

Clinical Relevance

  • MRI studies demonstrate diagnostic accuracy of 77%-92% for detecting ATFL tears, with the ATFL being identified as torn far more frequently than other lateral ligaments 3, 4
  • The American College of Radiology states that the anterior drawer test specifically detects ATFL injury by demonstrating excessive anterior displacement of the talus 2

Common Pitfall

  • The American College of Radiology warns not to confuse lateral ankle sprains (inversion injuries affecting ATFL) with high ankle sprains (syndesmotic injuries from dorsiflexion-eversion-external rotation) 1, 2

REFERENCES

1

acr appropriateness criteria® acute trauma to the ankle. [LINK]

Journal of the American College of Radiology, 2020

2

Ankle Sprain Definition and Characteristics [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

3

acr appropriateness criteria<sup>®</sup> chronic ankle pain. [LINK]

Journal of the American College of Radiology, 2018

4

acr appropriateness criteria<sup>®</sup> chronic ankle pain. [LINK]

Journal of the American College of Radiology, 2018