Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/26/2025

Management of Sertraline Overdose

Indications and Dosage

  • The American Academy of Pediatrics recommends administering activated charcoal in doses of 1-2 g/kg orally or via nasogastric tube in cases of sertraline overdose 1
  • Formulations of activated charcoal often contain sorbitol as a cathartic, and cases of hypernatremic dehydration have been reported after repeated doses of charcoal with sorbitol 1