Buspar Dosing Guidelines

Initial Dosing and Titration

The American Academy of Family Physicians recommends starting buspirone at 5 mg twice daily (total 10 mg/day) and increasing by 5 mg per day every 2-3 days until reaching the target dose of 15-30 mg/day divided into 2-3 doses, with a maximum of 60 mg/day 1
Begin with 5 mg twice daily (morning and evening) for the first few days, as recommended by the American Academy of Family Physicians 1
Increase by 5 mg per day every 2-3 days until therapeutic effect is achieved, according to the American Academy of Family Physicians 1
Most patients respond to 15-30 mg/day divided into 2-3 doses, as stated by the American Academy of Family Physicians 1
The maximum recommended dose is 60 mg/day (can be given as 20 mg three times daily), as recommended by the American Academy of Family Physicians 1

The American Academy of Family Physicians suggests using standard dosing for elderly patients but monitoring more carefully for side effects 1
The 5 mg twice daily starting dose is particularly appropriate for older adults, according to the American Academy of Family Physicians 1