Azilsartan for Hypertension: Clinical Efficacy and Recommendations

Introduction to Azilsartan Therapy

The International Society of Hypertension recommends ARBs like azilsartan as part of first-line therapy for hypertension, particularly in specific populations such as those with chronic kidney disease 1

For patients with hypertension and chronic kidney disease, ARBs like azilsartan are recommended first-line drugs because they reduce albuminuria in addition to blood pressure control 1
In patients with hypertension and coronary artery disease, RAS blockers like azilsartan are recommended as first-line therapy, with a target blood pressure of <130/80 mmHg (<140/80 in elderly patients) 1
For patients with hypertension and heart failure, ARBs are effective in improving clinical outcomes, with a target blood pressure of <130/80 mmHg but >120/70 mmHg 1

In resistant hypertension, azilsartan may be particularly effective as part of a multi-drug regimen due to its potent AT1 receptor blockade 2