Maximum Recommended Dose of Cefazolin for Pediatric Patients

Dosing Guidelines for Cefazolin in Pediatric Patients

• The maximum recommended dose of cefazolin for pediatric patients is 150 mg/kg/day divided into three doses (every 8 hours), with no established absolute maximum daily dose in milligrams 1, 2, 3
• For methicillin-susceptible Staphylococcus aureus infections, the preferred dosage is 150 mg/kg/day divided every 8 hours 1, 4, 5, 6

Specific Clinical Scenarios

• For infective endocarditis in pediatric patients, cefazolin should be dosed at 100 mg/kg per 24 hours IV in 3 equally divided doses 7, 8, 9