Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/17/2025

Ketoconazole Shampoo for Pediatric Scalp Fungal Infections

Application and Dosage

  • The American Academy of Pediatrics recommends leaving ketoconazole shampoo on for 3-5 minutes before rinsing thoroughly 1

Alternative Treatments

  • For systemic or invasive fungal infections, the Infectious Diseases Society of America recommends systemic antifungal therapy with agents like amphotericin B or fluconazole 2
  • For esophageal or oropharyngeal candidiasis, the Infectious Diseases Society of America recommends systemic therapy 3, 2
  • For cutaneous candidiasis, the American Academy of Pediatrics recommends clotrimazole 1% cream applied 2-3 times daily for 7-14 days 2, 1
  • For resistant or extensive cutaneous fungal infections, the American Academy of Pediatrics recommends oral fluconazole 3-6 mg/kg daily for 7 days 1

REFERENCES

1

Topical Treatment of Anal Yeast Infections in Children [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

Clotrimazole Use in Infants for Fungal Skin Infections [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025