Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/5/2025

Nerve Block and Trigger Point Injections for Neuralgia and Myalgia

Assessment of Medical Necessity

  • Peripheral nerve blocks are considered to have insufficient evidence for the treatment or prevention of headaches, including migraine headaches, according to the American Society of Anesthesiologists 1, 2
  • Peripheral nerve blocks should only be used for chronic pain as part of an active component of a comprehensive pain management program, as recommended by the American Society of Anesthesiologists 1
  • The American Society of Anesthesiologists notes that patients with chronic migraine without aura require a comprehensive pain management approach, which may include nerve blocks, but only as part of a larger program 3, 4

Evidence Analysis

  • Multiple guidelines, including those from the American Society of Anesthesiologists, indicate insufficient evidence for peripheral nerve blocks for headache management, with a lack of standardization in techniques, types, and doses of local anesthetics used 2, 5
  • The American Society of Anesthesiologists recommends against trigger point injections for chronic low back pain without radiculopathy, citing a lack of evidence for long-term benefit 3
  • The American Society of Anesthesiologists notes that peripheral somatic nerve blocks should not be used for long-term treatment of chronic pain, and that trigger point injections may provide short-term relief but lack evidence for long-term benefit 6, 7, 8, 5

Clinical Considerations

  • The American Society of Anesthesiologists recommends that patients with chronic pain receive comprehensive pain management, which may include preventive therapy, acute treatment, and alternative approaches, such as combination therapies 1, 4, 6

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