Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/15/2025

Indications for Continuing Bladder Irrigation

Primary Indications

  • Continuous bladder irrigation (CBI) should be used for patients with hematuria to prevent catheter obstruction from blood clots, particularly following urological procedures or in cases of severe bladder hemorrhage 1, 2
  • Postoperative bladder irrigation with antiseptics like chlorhexidine or povidone-iodine has been shown to reduce postoperative catheter-associated bacteriuria in patients undergoing transurethral operations 2, 3

Active Hematuria Management

  • Severe hematuria requiring clot prevention, especially when there is risk of urinary retention from clot formation 1, 4
  • Macroscopic hematuria with indwelling catheter requires CBI and possible endoscopic hemostasis treatment if necessary 1

Monitoring and Adjustment Parameters

When to Continue CBI

  • Persistent visible hematuria in the drainage bag 2, 4
  • Presence of urease-producing organisms in catheter biofilm that may cause catheter blockage (particularly Proteus mirabilis) 2, 3

When to Discontinue CBI

  • Resolution of hematuria with clear urine output 2, 4
  • Stabilization of bleeding parameters 1

Special Considerations

Antimicrobial Considerations

  • Routine addition of antimicrobials or antiseptics to the drainage bag is not recommended to reduce catheter-associated bacteriuria or UTI 2

Management of Continuous Bladder Irrigation in Women

Evidence Against Routine Bladder Irrigation

  • The Infectious Diseases Society of America recommends against routine catheter irrigation with antimicrobials or other agents to reduce catheter-associated bacteriuria or UTI in patients with long-term indwelling catheterization (Grade A-I recommendation) 5
  • Routine continuous bladder irrigation does not benefit women with long-term catheters in terms of reducing catheter obstruction rates, febrile episodes, or prevalence of bacteriuria 5

Indications for Bladder Irrigation

  • The American College of Physicians and other guideline societies support the use of continuous bladder irrigation for women with active hematuria to prevent catheter obstruction from blood clots, particularly following urological procedures 5
  • Bladder irrigation with antiseptics may be beneficial in preventing catheter-associated bacteriuria in surgical patients with short-term catheterization, although evidence is primarily from studies in men 5

Clinical Recommendations

  • For women with long-term catheters, do not perform routine bladder irrigation and do not add antimicrobials or antiseptics to drainage bags 5
  • For women with active hematuria, initiate continuous bladder irrigation with sterile normal saline and continue until hematuria resolves 5