Optimal Oocyte Retrieval for IVF

Fertility Preservation Context

• In cancer patients undergoing fertility preservation, a mean oocyte retrieval of 11.27 oocytes per patient has been reported with ovarian tissue cryopreservation combined with in vitro maturation (OTO-IVM), according to the American Society of Clinical Oncology 1, 2
• Standard ovarian stimulation in this population yields approximately 6.8 ± 4.6 oocytes when vitrified, as recommended by the American Society of Clinical Oncology 1

Critical Pitfalls to Avoid

• Retrieving significantly more than 13-15 oocytes does not improve pregnancy rates and increases risks of ovarian hyperstimulation syndrome (OHSS), which can cause capillary leak syndrome, thrombosis, and renal failure, as warned by the American College of Obstetricians and Gynecologists 4