Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Solifenacin for Overactive Bladder Treatment

Clinical Applications

  • Solifenacin is used in combination therapy with tamsulosin for men with both storage and voiding lower urinary tract symptoms 1
  • The European Association of Urology guidelines mention solifenacin as an effective antimuscarinic agent for treating storage symptoms in patients with lower urinary tract symptoms 2, 3

Therapeutic Considerations

  • The American College of Physicians recommends solifenacin as an effective option for reducing episodes of urgent urinary incontinence 4

Combination Therapy

  • The combination of solifenacin and tamsulosin in a single tablet has shown efficacy and safety for treating lower urinary tract symptoms in men 1, 5

Solifenacin Treatment for Overactive Bladder

Clinical Applications

  • The European Association of Urology guidelines recognize solifenacin as an effective antimuscarinic agent for treating storage symptoms in patients with lower urinary tract symptoms, and it may be used in combination therapy with β3-adrenoceptor agonists for patients refractory to monotherapy 6, 7