Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/20/2025

Complications of DAO Botox Injections

Common and Serious Complications

  • Dry mouth can occur due to effects on salivary production, as reported by the Centers for Disease Control and Prevention (CDC) 1
  • Dysphagia, or difficulty swallowing, can occur if toxin diffuses to muscles involved in swallowing, according to the American Academy of Otolaryngology-Head and Neck Surgery Foundation 2
  • Aspiration risk is related to dysphagia, particularly in patients with pre-existing neuromuscular disorders, as noted by the American Academy of Otolaryngology-Head and Neck Surgery Foundation 2 and further supported by similar findings 3
  • Patient education is crucial, as most side effects are temporary and will resolve as the toxin effect diminishes, typically within 3-6 months, as recommended by the American Academy of Otolaryngology-Head and Neck Surgery Foundation 3
  • Supportive care, including monitoring of respiratory function, may be necessary for patients experiencing dysphagia or other functional issues, as suggested by the CDC 4
  • Psychological support should be provided to address patient concerns about facial asymmetry or other visible effects, as recommended by the CDC 1
  • Informed consent is essential, and patients should be made aware of the potential complications and their temporary nature, as emphasized by the American Academy of Otolaryngology-Head and Neck Surgery Foundation 3

REFERENCES

2

clinical practice guideline: hoarseness (dysphonia). [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2009

3

clinical practice guideline: hoarseness (dysphonia). [LINK]

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2009