Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/28/2025

Holy Basil for Stress Control

Patient Characteristics and Response

  • Adults aged 18-65 years with perceived stress, with a mean age of 38.4 years, showed the best documented response to holy basil supplementation 1

Safety and Precautions

  • The American Journal of Kidney Diseases reports that holy basil may have sedative properties, increasing the total sleep time induced by diazepam in a dose-dependent manner, and may interact with anesthetics 1
  • The American Journal of Kidney Diseases also notes that holy basil may have cardiovascular effects, such as reducing blood pressure, and recommends monitoring blood pressure in patients with a history of cardiovascular disease 1

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