Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/3/2025

Recommended Health Screenings for Adults

Cardiovascular Risk Assessment

  • The American College of Cardiology recommends blood pressure measurement at every clinical encounter for adults of all ages 1
  • Annual lipid profile screening is indicated for men aged 40-49 years to assess cardiovascular risk 1
  • Men aged 40-49 years require annual blood pressure measurement and lipid profile screening to assess cardiovascular risk 1

Cancer Screening

  • Colorectal cancer screening should have already begun at age 45 with one of the following options: annual fecal immunochemical test (FIT), colonoscopy every 10 years, or CT colonography every 5 years 1, 2
  • The American Cancer Society recommends against PSA testing at age 48 for average-risk men, as the harms of PSA-based screening and overtreatment outweigh potential benefits 3, 4
  • Exception: African American men or those with strong family history should have screening discussion at age 45 2

Laboratory Testing

  • Complete blood count (CBC) and comprehensive metabolic panel (CMP) are not routinely indicated at this age without specific clinical indications 1, 4

Critical Pitfalls to Avoid

  • Do not order PSA testing at age 48, as it provides no benefit for average-risk men and leads to unnecessary anxiety, biopsies, and overtreatment of indolent disease 3, 4
  • Do not perform routine comprehensive metabolic panels or CBCs without clinical indication, as this leads to false positives and unnecessary follow-up 4
  • Do not skip colorectal cancer screening, as this should have already begun at age 45 and is critical for mortality reduction 1, 2

REFERENCES

1

Routine Laboratory Screening by Age Group [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

Colorectal Cancer Screening Guidelines for Average-Risk Individuals [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

4

Health Screenings for Young Adults [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025