Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/31/2025

Hormones That Induce Labor

Safety Considerations

  • The risk of uterine rupture with oxytocin is approximately 1.1%, which is lower than with prostaglandins 1

Clinical Applications Beyond Labor Induction

  • In women with respiratory disease, oxytocin is the uterotonic of choice for active management of the third stage of labor, as alternatives like ergotamine may cause bronchospasm 2, 3