Substances That Slow Vyvanse Breakdown

Clinical Approach and Safety Considerations

• Attempting to alter the breakdown of Vyvanse could lead to unpredictable cardiovascular stress and increased risk of adverse effects, as the medication already increases heart rate and blood pressure, according to Praxis Medical Insights 1
• Alcohol should be completely avoided while taking Vyvanse, as it creates unpredictable cardiovascular stress and the prodrug mechanism may be affected by alcohol's impact on hepatic metabolism, as recommended by Praxis Medical Insights 1
• The American College of Obstetricians and Gynecologists recommends titrating the dose by 10 mg weekly increments to a maximum of 70 mg daily, as recommended for standard dosing 2
• The Centers for Disease Control and Prevention suggests discussing any new medications or supplements with your healthcare provider, as careful attention should be given to relative risks versus benefits of specific combinations 7