Normal Fasting Plasma Glucose Levels

Definition of Normal Fasting Plasma Glucose

The American Diabetes Association (ADA) defines normal fasting plasma glucose as less than 100 mg/dL (5.6 mmol/L) 1
The World Health Organization (WHO) previously defined normal glucose regulation as FPG < 6.1 mmol/L (110 mg/dL), which is different from the current ADA criteria 3

The American Diabetes Association (ADA) categorizes glucose metabolism as normal (FPG < 100 mg/dL or 5.6 mmol/L), impaired fasting glucose (FPG 100-125 mg/dL or 5.6-6.9 mmol/L), and diabetes mellitus (FPG ≥ 126 mg/dL or 7.0 mmol/L) 1, 2, 4

Fasting plasma glucose should be measured after at least 8 hours of no caloric intake, as recommended by the American Diabetes Association (ADA) 2
The American Academy of Family Physicians recommends confirming values by repeat testing on a different day to establish a diagnosis of diabetes or prediabetes 4

The European Heart Journal notes that plasma glucose values are approximately 11% higher than whole blood glucose values 3
The American Academy of Family Physicians recommends fasting plasma glucose as the preferred initial test for screening purposes due to convenience and cost-effectiveness 4
The American Diabetes Association (ADA) suggests that patients with normal FPG but risk factors for diabetes may benefit from additional testing with oral glucose tolerance test or HbA1c 1