L-Arginine and Citrulline Supplementation for Exercise Performance

Mechanism of Action and Benefits

• Both L-arginine and L-citrulline function as precursors to nitric oxide (NO), a potent vasodilator that may enhance blood flow to muscles during exercise, as recommended by the American College of Sports Medicine 1

Safety Considerations

• Both supplements are generally well-tolerated at recommended dosages, according to the International Society of Sports Nutrition 2

Dosage Recommendations

• Effective dosages of L-citrulline range from 1.2-6g daily, with most performance benefits observed at 3-6g daily, as suggested by the National Academy of Sports Medicine 2