FSH Range for Perimenopause

Clinical Guideline Recommendations

• The National Comprehensive Cancer Network defines menopause as requiring amenorrhea for ≥12 months with FSH and estradiol in postmenopausal ranges for women under age 60 1
• For women over 60 years, menopause can be diagnosed without hormone testing 1

When FSH Testing May Be Appropriate

• Women under 60 who are amenorrheic for ≤12 months and considering hormone therapy may require FSH monitoring, as recommended by the National Comprehensive Cancer Network 2, 3
• FSH monitoring is recommended after chemotherapy to assess ovarian function, according to the National Comprehensive Cancer Network 2, 3
• When switching from tamoxifen to aromatase inhibitors in breast cancer patients, FSH monitoring may be necessary, as suggested by the National Comprehensive Cancer Network 2, 3
• Testing should include both FSH and estradiol measured concurrently, with low estradiol and high FSH supporting postmenopausal status, as noted by the National Comprehensive Cancer Network 1