Quetiapine Use During Breastfeeding

Monitoring and Safety Precautions

• The American Academy of Pediatrics recommends monitoring the infant for increased sleepiness, poor feeding, decreased alertness, or any signs of sedation when the mother is taking quetiapine during breastfeeding, due to the potential risk of sedation 1, 2

Pharmacokinetics and Infant Exposure

• The estimated infant dose of quetiapine represents only a small percentage of the weight-adjusted maternal dose, with calculated infant daily doses ranging from less than 0.01 mg/kg to 0.1 mg/kg, suggesting minimal risk to the breastfed infant 1, 2