Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/6/2025

COVID-19 Infection Control in Nursing Homes

Testing Strategy

  • Conduct weekly testing of all residents and staff in facilities without active outbreaks using rapid antigen tests or PCR testing 2, 4, 5
  • Increase testing frequency to every 3 days once a single COVID-19 case is identified in the facility 2, 4
  • Use nasopharyngeal swabs for SARS-CoV-2 testing via RT-PCR or rapid antigen tests 6
  • Rapid antigen tests are preferred when available due to immediate results enabling faster cohorting 2, 4

Isolation and Cohorting Protocols

  • Isolate COVID-19 positive residents in well-ventilated single rooms when possible, or maintain at least 1 meter bed distance if single rooms are unavailable 7, 8, 9
  • Physically separate COVID-19-positive residents from others in a separate area of the facility 1, 2, 4
  • Assign dedicated staff to work exclusively in the COVID-19 cohort to prevent cross-contamination 1, 2, 4

Personal Protective Equipment (PPE) Requirements

  • All staff must wear masks, gowns, gloves, and eye protection when caring for COVID-19 positive residents 1, 2, 4
  • Staff should wear N95 masks (preferred) or surgical masks when in the same room as infected residents 7, 8, 10

Environmental Infection Control

  • Clean and disinfect all high-touch surfaces using 500 mg/L chlorine-containing disinfectant frequently every day 7, 8, 10
  • Open windows for ventilation in shared areas such as toilets and kitchens 7, 10

Treatment Protocols

  • Administer Paxlovid or other available antivirals to eligible residents as soon as possible after positive test and within 10 days of symptom onset to reduce probability of death 2, 3
  • Monitor vital signs regularly including temperature, heart rate, respiratory rate, and oxygen saturation 8, 9, 10

Vaccination Strategy

  • Ensure all residents receive COVID-19 vaccination as the primary prevention strategy - vaccination dramatically reduced case fatality rates even with highly transmissible variants like Omicron 2, 3

Monitoring and Quality Assurance

  • Contract with at least a part-time infection control specialist as required by CMS 1, 2
  • Track facility infection rates relative to surrounding community levels 1, 2