Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/26/2025

Immunization Schedule for 2-Month Well Visit

  • The American Academy of Pediatrics recommends that infants receive DTaP, Hib, PCV, IPV, Rotavirus, and the second dose of Hepatitis B vaccines at the 2-month well visit to protect against serious infectious diseases 1, 2, 3
  • The Centers for Disease Control and Prevention (CDC) advises that the second dose of Hepatitis B vaccine should be given at the 2-month well visit, as part of the standard immunization schedule 3
  • The CDC recommends the first dose of Diphtheria, Tetanus, and acellular Pertussis (DTaP) vaccine at the 2-month well visit 1, 2, 3
  • The CDC recommends the first dose of Haemophilus influenzae type b (Hib) vaccine at the 2-month well visit 1, 2, 3
  • The CDC recommends the first dose of Pneumococcal conjugate vaccine (PCV) at the 2-month well visit 1, 2, 3
  • The CDC recommends the first dose of Inactivated Poliovirus (IPV) vaccine at the 2-month well visit 1, 2, 3
  • The CDC recommends the first dose of Rotavirus vaccine at the 2-month well visit 3

Special Considerations

  • For infants born to HBsAg-positive mothers, the CDC recommends ensuring proper follow-up of the hepatitis B vaccination series that began at birth with both HepB vaccine and HBIG (Hepatitis B Immune Globulin) 4, 5, 6
  • For preterm infants weighing less than 2,000 grams, the CDC advises that the birth dose of HepB should not be counted in the series; they will need a total of 4 doses 4, 5
  • If using PRP-OMP (PedvaxHIB) for Hib vaccination, note that this requires only 2 primary doses (at 2 and 4 months) rather than 3 doses with other Hib vaccines 2