Ketorolac-Associated Renal Complications

Patient Risk Factors

The risk of acute renal failure is particularly elevated in patients with marginal baseline kidney function, such as those with sickle cell crisis, according to the American Medical Association 1, 2
Patients ≥60 years of age require cautious use, as recommended by Praxis Medical Insights 3
Those with compromised fluid status or pre-existing renal impairment are at increased risk, as noted by Praxis Medical Insights 2, 3
Patients on concomitant nephrotoxic drugs should be monitored closely, as advised by Praxis Medical Insights 3

When initiating ketorolac therapy, monitor baseline and periodic BUN and creatinine, as recommended by Praxis Medical Insights 3
Limit treatment duration to ≤5 days to minimize renal complications, as advised by Praxis Medical Insights 3
Use maximum daily dose of 120 mg in adults and avoid exceeding recommended dosing, as recommended by Praxis Medical Insights 3