Tapering Escitalopram

Introduction to Tapering

All SSRIs, including escitalopram, must be slowly tapered when discontinued due to the risk of withdrawal effects, as recommended by the American Academy of Pediatrics 1, 2

Protracted withdrawal may include dysphoria, irritability, insomnia, anhedonia, or a vague sense of being unwell that can persist for months after complete discontinuation, according to the Mayo Clinic 3
If intolerable symptoms occur, consider extending the time between dose reductions to 4-6 weeks, as suggested by medical guidelines 4
Consider smaller dose reductions (5% instead of 10%) to minimize withdrawal symptoms 4

Consider symptomatic treatments as needed, such as trazodone or mirtazapine for insomnia, NSAIDs or acetaminophen for headaches and muscle aches, and anti-nausea medications for gastrointestinal symptoms, as recommended by medical guidelines 5

Schedule appointments every 2-4 weeks during the taper to assess for withdrawal symptoms and potential relapse, and document baseline symptoms and functioning before initiating the taper, as suggested by medical guidelines 4
Continue monitoring for several months after complete discontinuation for protracted withdrawal symptoms 5
Be prepared to adjust the tapering schedule based on individual patient response, as recommended by medical guidelines 4