Guidelines for Administering Clinimix

Indications and Formulation

Clinimix is a parenteral nutrition solution composed of carbohydrates, amino acids, and can include electrolytes, vitamins, and trace elements as required, according to the Clinical Nutrition guidelines 2, 3
It is indicated when the oral or enteral route cannot independently achieve the defined nutritional care plan target, as stated by the Clinical Nutrition guidelines 4
Clinimix can be used as total parenteral nutrition (TPN) when the patient's complete nutritional needs are covered intravenously, or as supplemental parenteral nutrition (SPN) when nutrition is also provided via oral or enteral routes, as recommended by the Clinical Nutrition guidelines 4, 3

Central venous access is recommended for high osmolarity Clinimix formulations designed to cover nutritional needs fully, according to the Clinical Nutrition guidelines 1
Peripheral venous access may be used for low osmolarity mixtures designed to cover a proportion of nutritional needs, as stated by the Clinical Nutrition guidelines 1
If peripherally administered PN does not allow full provision of the patient's needs, then PN should be centrally administered, as recommended by the Clinical Nutrition guidelines 1

For adults, the recommended daily nutritional requirements are typically 25 kcal/kg/day, increasing to target over 2-3 days, according to the Clinical Nutrition guidelines 1

Hyperglycemia contributes to increased mortality in critically ill patients and should be avoided to prevent infectious complications, as stated by the Clinical Nutrition guidelines 1
Cutting or splitting Clinimix bags that aren't designed to be divided can lead to inconsistent dosing and potential degradation of the solution, according to Praxis Medical Insights 5