Fertility Treatment for Women with Low AMH

Introduction to Low AMH and Fertility

• Women with low AMH (<1.0 ng/ml) have a 28% increased relative risk of miscarriage (OR 1.28, 95% CI 1.07-1.53) 1
• Women with severely low AMH (<0.7 ng/ml) face 91% increased odds of miscarriage (OR 1.91) 2, 3, 1
• In women ≥35 years, low AMH confers 85% increased miscarriage risk 4, 1

Counseling and Treatment Recommendations

• The American Society for Reproductive Medicine recommends women with AMH <1 ng/ml pursue fertility evaluation and attempts promptly 4, 1
• Women with low AMH should be counseled about significantly reduced fertility potential and elevated miscarriage risk 4, 1
• Consider fertility preservation options (oocyte cryopreservation) before any planned surgeries 4
• Set realistic expectations: while pregnancy is possible, likelihood is significantly reduced 1