Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/29/2025

Iron and Zinc Supplementation Guidelines

Administration and Timing

  • Take zinc supplements 30 minutes before meals for optimal absorption 1, 2
  • Take Maltofer with food to improve tolerability and reduce gastrointestinal side effects 2

Monitoring and Precautions

  • Monitor serum zinc levels and alkaline phosphatase periodically, especially with concurrent iron supplementation 1, 3
  • Monitor copper status when taking 30 mg daily zinc, as high zinc intakes can induce copper deficiency 2
  • Assess iron status (ferritin, hemoglobin) to ensure adequate iron absorption despite separated dosing 3
  • Do not take zinc with fluoroquinolone antibiotics (like moxifloxacin), as zinc reduces their absorption 4