Fluconazole and Liver Function in Healthy Individuals

Monitoring Recommendations

• The British Association of Dermatologists recommends baseline liver function tests before starting fluconazole therapy, particularly in patients with pre-existing liver dysfunction, those receiving high-dose or prolonged therapy, and patients taking concomitant hepatotoxic drugs 1, 2
• Clinical guidelines recommend monitoring hepatic enzymes before starting fluconazole, at 2 and 4 weeks after initiation, and every 3 months during therapy, as recommended by clinical guidelines from the British Association of Dermatologists 3