Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/30/2025

Management of Pain in Patients with History of Gastric Varices and Peptic Ulcer Disease

Clinical Considerations

  • Peptic ulcer perforation is a life-threatening surgical emergency with mortality rates of up to 30% 1
  • Patients with a history of peptic ulcer perforation should be monitored for Helicobacter pylori infection and treated if positive 2