Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/2/2025

Management of Rhinitis Sicca

First-Line Treatment Approach

  • The American College of Allergy, Asthma, and Immunology recommends nasal saline irrigation as the cornerstone of rhinitis sicca management, used 2-3 times daily, with hyaluronic acid-based nasal sprays or ectoine-containing preparations as effective adjunctive moisturizing agents 1
  • Regular nasal saline irrigation is the primary treatment modality, providing mechanical moisturization, crust removal, and symptom relief in patients with dry nasal mucosa 1

Adjunctive Medical Management

  • The American Academy of Allergy, Asthma, and Immunology suggests using intranasal corticosteroids with caution in rhinitis sicca, as topical corticosteroids may potentially worsen nasal dryness despite their anti-inflammatory properties 1
  • If inflammation is a significant component, use the lowest effective dose and monitor the nasal septum periodically for mucosal erosions, as recommended by the American College of Allergy, Asthma, and Immunology 2
  • Direct spray away from the nasal septum to minimize risk of mucosal damage, according to the American College of Allergy, Asthma, and Immunology 2
  • Anticholinergic agents are not recommended as primary therapy for rhinitis sicca, since ipratropium bromide is specifically indicated for rhinorrhea, not dryness, as stated by the American College of Allergy, Asthma, and Immunology 2

Common Pitfalls to Avoid

  • The American Academy of Otolaryngology recommends avoiding topical decongestants, as they will further dry the nasal mucosa and risk rhinitis medicamentosa 2
  • Avoid prolonged use of intranasal corticosteroids alone without adequate moisturization, as this can exacerbate dryness, according to the American College of Allergy, Asthma, and Immunology 1
  • Do not prescribe oral antihistamines, which have anticholinergic effects that worsen nasal dryness, as recommended by the American Academy of Allergy, Asthma, and Immunology 2

REFERENCES

1

Management of Empty Nose Syndrome [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025