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Last Updated: 9/20/2025
Corticosteroid-Induced Leukocytosis
Special Patient Populations
In patients with acute promyelocytic leukemia (APL), an increase in WBC count above 10 × 10^9/L after treatment initiation with ATRA and/or ATO should be interpreted as a sign of treatment-induced differentiation and not reclassification as high-risk disease 1, 2