Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

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Last Updated: 7/7/2025

Management of Botox-Induced Ptosis

Introduction to Ptosis

  • Ptosis, or drooping of the upper eyelid, is a recognized complication of Botox injections, typically occurring 3-14 days after treatment, creating a hooded appearance with asymmetry between eyes, and possible visual field impairment or double vision (diplopia) in severe cases 1, 2

Assessment and Initial Management

  • The American Academy of Ophthalmology recommends assessing the severity of ptosis to determine if it's affecting vision or causing significant cosmetic concerns, and documenting with photos if possible for comparison during treatment 1
  • Applying cold compresses for 10-15 minutes several times daily can help reduce swelling, and patients should avoid pressure directly on the eyelid 1
  • Maintaining an upright position for at least 3-4 hours after treatment and avoiding bending over or lying down immediately after injection can also help reduce swelling 1, 3
  • Patients should avoid touching, rubbing, or massaging the treated areas, refrain from strenuous exercise for 24 hours, and avoid alcohol consumption for 24 hours to reduce the risk of ptosis 3

Medical Management

  • The American Society for Dermatologic Surgery recommends consulting with a healthcare provider, such as an ophthalmologist, within 1 week for mild cases of ptosis, and using artificial tears for lubrication 1
  • Apraclonidine 0.5% eye drops can be used as primary treatment, working by stimulating Müller's muscle to contract and elevate the upper eyelid, with typical dosing of 1 drop in affected eye(s) 2-3 times daily 1, 3
  • For accompanying diplopia, temporary occlusion (eye patch) or prisms (press-on or ground-in) can be used to manage double vision while waiting for resolution 2, 3

Ongoing Management and Prevention

  • Regular monitoring every 1-2 weeks to assess improvement and continuing apraclonidine drops if effective can help manage ptosis 1, 3
  • Choosing practitioners with thorough knowledge of facial anatomy and ensuring they use proper technique and conservative dosing can help prevent ptosis 1, 2
  • Pre-treatment documentation of eyelid position and discussing history of ptosis with the provider before any future treatments can also help prevent ptosis 1, 3
  • Patients should be informed of the potential side effect of ptosis before treatment, and thorough anatomic knowledge of the supraorbital area and orbital roof is essential for practitioners to avoid "danger zones" 3
  • The onset of ptosis is usually characterized by a temporary and self-resolving condition, with a duration that typically matches the expected duration of the botulinum toxin effect (3-4 months) 3